Safe Mode actualy did allow both programs to load, albeit in a woefully terrible and unusable screen resolution. Furthermore, looking at the Windows Event Viewer shows that both Photoshop and Poser are crashing due to an issue with the same file: NTDLL.DLL

 

Currently using Poser Pro 2012 (Display Units = feet)

AMD Phenom II 3.2ghz (6 cores)

8gb RAM

Windows 10 Pro 64bit