I find the best use of the guide curves is to enclose an area as opposed to outline exact muscle structure. This leaves the program free to do its thing while still getting the zones you want for easier projection of detail.  Ultimately that's what ZRemesher is all about. It's primary use will be to get a mesh from either a Dynameshed model or one that has poor layout for certain details) that you can get cleaner details with fewer subdivisions during the reproject process. At least that'll be my primary use before using the mesh to continue my sculpting. Technically, in theory, you could create a model for use in Poser with it but you may run into some odd layouts that would be hard to get around depending on how you've put down your guides or if you used any at all.  I will say for non-humanoid animals, it has so far proven very intelligent in its creation of topology. Dragons and quadropeds in particular on my end.