it depends on what you want to do.

the way most people make clothes makes them look like butt with procedural textures (such as bagginsbill's Matmatic Loom materials).  making them like real clothes gives you a good basis for procedural textures and allows you to create something that works really well as dynamic clothing.  that said, i have no clue how that works with cloth that  works like skin instead of cloth (or other materials).  personally, i don't find conforming clothing very convincing when it does that, so my goal is avoid it altogether, but that's just me.