I think you need to experiment with a short piece of animation. If the animation will be looked at at a distance you normally use a display (is it an Aple Cinema Display, the one I am looking at right now?) my first thought would be that you need to render the same size. But that is a LOT of render time. When you switch a Cinema Display to a smaller screen resolution (like 1280x800), things get blurred a little, but when you take a step backwards, this should not be a problem. Enlarging from smaller sizes should result in a more blurred image. So, the larger, the better. Maybe you can cheat by putting a border around the animation, or to embed it in a static background or someting. If you really want no loss in quality, you'd better start lining up them processors for network rendering... Maybe that 'no quality loss' somewhere hits a wall that says 'not possible'... This will be a heavy load to render, to store and to play. I do not know what kind of animation it is, but I personally would really search for alternatives (Vectorstyl & Flash ?) if it is just a 'flying logo' type of thing or do lots of tests to discover how many years of rendering, how many gigs of hard disk space and money is needed to make this happen.